DNA Sequencing

Choose from a broad range of DNA sequencing lasers and light engines for high-throughput applications as well as research and clinical uses.

More Power Get the power you need with our power-scalable laser technologies.
More Wavelengths Select the exact wavelength(s) you need with our unique OPSL technology.
Less Hassle Eliminate your design hassles with light engines combining two or more wavelengths.

Fluorescence Detection

There are numerous methods available as commercial instruments, optimized for whole genome sequencing (WGS) targeted sequencing and other applications. They all rely on some type of light detection: usually lasers excited fluorescence or bioluminescent enzymes. Key laser parameters are usually low-noise and high reliability. Coherent offers a wide range of OEM lasers that emphasize these characteristics, with numerous wavelength choices and power from 10s of milliwatts to several watts.

DNA Sequencing Products

Sapphire

Sapphire CW lasers provide industry-leading beam quality, reliability, and stability with up to 500 mW of low-noise output for OEMs and end-users.

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OBIS LS/LX

OBIS LS/LX are the original compact smart lasers, offering plug-and-play simplicity with over 30 wavelengths from the UV to near-IR plus optional fiber delivery.

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Laser Light Engines

Coherent Laser Light Engines simplify your multi-wavelength applications with a pre-aligned laser light engine with free-space or fiber-coupled output.

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Genesis

With wavelengths from 355 to 1154 nm and power from 100 mW to 10 W, these lasers support diverse applications: life sciences, medical, FPDs, interferometry/holography.

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StingRay and BioRay

StingRay and BioRay diode laser modules are compact lasers with fiber-ready (FR) or elliptical beam output and user-adjustable focus, ideal for particle counting.

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Laser Microscopes are Key Tools in Biology

Discover why confocal microscopy, multiphoton microscopy, and super-resolution microscopy all rely on lasers to support cutting-edge research in life sciences.

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Cancer Cell Analysis — A New Vector

Sapphire Laser Family Hits 55,555 Units

Success Story

Politecnico di Milano

“The high reliability and operational simplicity of Coherent ultrafast lasers are critical advantages because of the optical and electronic complexities of our imaging method.”

— Giulio Cerullo, Professor of Physics, Politecnico di Milano, Italy.

Resource List

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Coherent

OPSL Advantages - Wavelength Flexibility White Paper

The Optically Pumped Semiconductor Laser (OPSL) technology offers numerous advantages over other types of CW lasers, including wavelength flexibility. In particular, an OPSL can be designed to match the wavelength requirements of the application, which represents a paradigm shift over legacy technologies.

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Coherent

OPSL Advantages - Invariant Beam Properties White Paper

The main technology choices for CW visible and near IR laser sources include DPSS lasers and OPSLs.

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Coherent

OPSL Advantages - No Mode Noise ("Green Noise") White Paper

The optically pumped semiconductor laser (OPSL) is a unique, patented technology that provides lower intrinsic noise than other continuous wave (CW) solid state lasers having UV or visible output, and is the only way to achieve true-CW output at 355 nm in a simple, cost-effective platform.

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Coherent

OPSL Advantages - Superior Reliability White Paper

The optically pumped semiconductor laser (OPSL) is a unique, patented technology that provides superior reliability and longevity compared to other continuous wave (CW) solid state lasers. Together with other OPSL advantages, this reliability is confirmed by an installed base approaching 100,000 lasers in diverse and demanding applications from life sciences to light shows.

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